Interplay Between the Histone Variant H2A.Z and the Epigenome in Pancreatic Cancer.
Ávila-López, P. A., Nuñez-Martínez, H. N., Peralta-Alvarez, C. A., Martinez-Calvillo, S., Recillas-Targa, F., & Hernández-Rivas, R. (2022). Interplay Between the Histone Variant H2A.Z and the Epigenome in Pancreatic Cancer. Archives of Medical Research, 53(8), 840?858. https://doi.org/10.1016/j.arcmed.2022.11.010
ABSTRACT
The oncogenic process is orchestrated by a complex network of chromatin remodeling elements that shape the cancer epigenome. Histone variant H2A.Z regulates DNA control elements such as promoters and enhancers in different types of cancer; however, the interplay between H2A.Z and the pancreatic cancer epigenome is unknown.